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Cannabis essential oil in a glas vial

Enhanced cannabis extraction equipment for better yield

A comprehensive GMP-compliant instrumentation portfolio for cannabis processing equipment

Over the past years, the cannabis industry has evolved into a multi-billion business. The range of cannabis-infused products, spanning beverages, snacks and medicine, is consistently expanding. As a result, the demand for cannabis extraction equipment has increased as well. Extracting the essential oil of the cannabis plant is a key step in the production process. The oil is then further processed and infused in different products. Instrumentation plays a crucial role along all process steps.

How we can help

Endress+Hauser offers a wide portfolio of technology and certifications that meets the requirements of the cannabis industry. Covering simple applications to high-temperature scenarios, from pressure sensors to conductivity measurements, as a sole provider we can deliver a comprehensive range of instrumentation. Numerous instruments come with ATEX and UL certification, coupled with hygienic process connections. Additionally, Endress+Hauser is a recognized brand in the life sciences industry.

  • Accurate and reliable measuring of the process conditions for precision extraction

  • Well-controlled extraction equipment to ensure product quality

  • Precise temperature measurement to avoid the coextraction of unwanted by-products

  • Precise flow measurement enables quantity-based recipe control to ensure consistent quality

Applications

Cannabis extraction under GMP guidelines

There are three different solvents that can be used to extract the desired compounds of the cannabis plant: ethanol, hydrocarbons and supercritical CO2. With different solvents come vastly different process conditions that impact the extracted cannabidiol oil or crude oil at the end of the extraction process. For example from -40 °C with ethanol to +55°C with hydrocarbon. Endress+Hauser has the right instrumentation to improve your extraction process with all three methods.

Essential oils of the cannabis plant
Our expertise in the field

Due to the significant impact on the product quality, the extraction process must be well-controlled. Our comprehensive instrumentation portfolio offers a wide range of technology to cover the entire extraction process, regardless of which specific method is applied. Our portfolio includes hygienic process connections and Ex certification as well as ceramic measuring cells.

  • The pressure in pipes and vessels is monitored by Cerabar PMC51B pressure sensors with ceramic membrane.

  • Precise flow measurement technology like the Promass E100 enables quantity based recipe control to ensure consistent quality.

  • Implementing accurate and reliable level measurement with our Liquiphant FTL63 ensures a more controlled and optimized extraction operation.

  • Precise temperature measurement is necessary to avoid the co-extraction of unwanted by-products. A temperature sensor with a very fast response time like our iTHERM QuickSens can improve the protection of temperature sensitive compounds.

Winterization & Filtration process

The winterized cannabis oil then goes through a vacuum filtration process. This crucial step separates the majority of ethanol from the oil, allowing for its reuse within a closed-loop system. The winterization process eliminates fats, lipids, and other undesirable substances from the crude oil extract. This step is essential to enhance the purity of cannabinoids.

Winterization process extracts undesirable substances from crude oil extract.
Our expertise in the field

Process conditions in this step can vary between -20°C and - 80°C for temperature and approximately 6 bar of pressure.

  • Our Micropilot FMR63B is a perfect fit for these process conditions and come with hygienic certifications such as ASME-BPE and various ex-certifications

Distillation with cannabis extraction equipment

The final stage involves the distillation process, utilizing a thin-film evaporator to further refine and purify the cannabis oil. This step enables precise control over the cannabinoid profile of the end product.

Distillation purifies the cannabis oil
Our expertise in the field

Accurate measurements of pressure, level and flow in this process step help control the key parameters that influence the separation and collection of the desired compounds.

  • The pressure in pipes and vessels is monitored by Cerabar PMC51B with ceramic membrane.

  • Dry run protection in circulation pumps is ensured with our vibronic point level detection Liquiphant FTL63. This point level switch is fit for use in hazardous areas as well as the hygienic certificates for the life sciences industry.

  • For 80GHz radar level measurement in application with hygiene requirements (3A, EHEDG, CoC ASME-BPE) our Micropilot FMR63B is an ideal candidate.

  • Coriolis mass flow meters such as Proline Promass F 300 ensure the correct dosage of the liquids.

ATEX, FM/UL, FDA, hygienic requirements

ATEX, FM/UL, FDA, hygienic requirements as well as safety-related requirements are thoroughly implemented in our entire portfolio. Due to the use of ethanol as a solvent the cannabis extraction equipment is subject to explosion protection. Depending on the country of destination, the equipment is certified according to ATEX or for the North American market according to FM/UL standard.

Factory calibration with certificates is standard at Endress+Hauser
Our expertise in the field

While GMP is not yet mandatory in these applications, all used Endress+Hauser devices posses the required approvals. To address customer concerns, our measuring devices have a hygienic design with FDA conformity for wetted parts. Factory calibration with certificates is the standard.

Cannabis processing

crude oil extraction systems ©Endress+Hauser

A DEVEX extraction system for the recovery of crude oil. This system extracts the active ingredients from cannabis with regard to the EU GMP guidelines enabled by Endress+Hauser instrumentation.

The different process conditions during extraction. ©Endress+Hauser

The process conditions for each cannabis extraction method.

Instrumentation portfolio for the extraction process. ©Endress+Hauser

Endress+Hauser Instrumentation Packages for Cannabis extraction.

Extraction plant builder DEVEX Verfahrenstechnik

Axel Remke, Senior Engineer Process bei DEVEX

Wir profitieren von der breiten Produktpalette von Endress+Hauser, einem einzigen Anbieter, der zahlreiche Lösungen für das Messprinzip anbieten kann.

Mr. Axel Remke

Senior Engineer Process, DEVEX Verfahrenstechnik GmbH

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